Jo Cameron, a woman from Scotland, possesses a rare genetic mutation that prevents her from feeling physical pain, anxiety, or fear. For decades, she remained unaware of the medical nature of her condition, attributing her lack of pain after major surgeries and injuries to personal toughness. Scientists discovered her condition is linked to a previously unidentified gene, dubbed “FAAH-OUT,” which regulates the signaling of pain and mood. This discovery offers potential breakthroughs for developing new, non-addictive pain management treatments. This report is a rebroadcast of a previously aired segment.
- Jo Cameron has lived her entire life without experiencing physical pain, including during childbirth and invasive medical procedures.
- The condition is caused by a rare mutation in the FAAH-OUT gene, which prevents the breakdown of anandamide, a chemical that regulates pain, mood, and memory.
- In addition to physical analgesia, Cameron reports a near-total absence of anxiety and fear, even in life-threatening situations.
- The genetic mutation also appears to facilitate faster wound healing with minimal scarring compared to the average person.
- Researchers at University College London believe studying this mutation could lead to the development of gene therapies for chronic pain and PTSD.
- The condition carries significant risks, as the subject frequently suffers burns or other injuries without immediate awareness.
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Original video here.
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